Rice University

Shared Equipment Authority

Mass Spectrometers

MS: Thermo LTQ-Orbitrap

The LTQ-Orbitrap system is equipped with ESI, nanoESI, and APCI sources. The LTQ-Orbitrap is a hybrid ion trap- FT (Fourier Transform) mass spectrometer capable of performing MS/MS experiments and making accurate mass measurements (maximum mass resolving power is 100,000 @ m/z 400).  This system is interfaced with a Shimadzu Prominence UPLC system. It is capable of performing analysis of synthetic compounds (ie. small molecules, synthetic peptides, impurity profiling, etc.) and biomolecules (ie. natural products, metabolites, peptides, proteins, oilgonucleotides, etc.).