Rice University

Shared Equipment Authority

Mass Spectrometry Facility

The Rice Core Mass Spectrometry Facility is operated by the Shared Equipment Authority (SEA) and located on the 2nd floor of the BioScience Research Collaborative (BRC). The facility has instrumentation capable of analyzing a wide variety of compounds. The two Bruker MS systems (Autoflex & MicroToF) along with the Perkin Elmer ICP systems (Optima & Nexion) are available to trained users, on a walk up basis. Facility staff also analyze samples and contribute to projects on a fee for service and collaborative basis. For additional questions or to request training please contact Dr. Christopher Pennington (clp5@rice.edu).

MS: Thermo LTQ-Orbitrap

The LTQ-Orbitrap system is equipped with ESI, nanoESI, and APCI sources. The LTQ-Orbitrap is a hybrid ion trap- FT (Fourier Transform) mass spectrometer capable of performing MS/MS experiments and making accurate mass measurements (maximum mass resolving power is 100,000 @ m/z 400).  This system is interfaced with a Shimadzu Prominence UPLC system. It is capable of performing analysis of synthetic compounds (ie. small molecules, synthetic peptides, impurity profiling, etc.) and biomolecules (ie. natural products, metabolites, peptides, proteins, oilgonucleotides, etc.).